Monday, 17 September 2012

Terazosin



Pronunciation: ter-AZ-oh-sin
Generic Name: Terazosin
Brand Name: Hytrin


Terazosin is used for:

Treating high blood pressure and treating signs and symptoms of benign prostatic hyperplasia (BPH).


Terazosin is an alpha-blocker. It works by relaxing muscles in the blood vessels, resulting in lowering of blood pressure. In BPH, alpha-blockers work by relaxing muscles around the urethra (tube that drains urine from the bladder), which improves urinary symptoms.


Do NOT use Terazosin if:


  • you are allergic to any ingredient in Terazosin or to similar medicines (eg, prazosin)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Terazosin:


Some medical conditions may interact with Terazosin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have prostate cancer, angina pectoris, heart disease, or kidney or liver problems

  • if you will be having eye surgery

Some MEDICINES MAY INTERACT with Terazosin. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Phosphodiesterase type 5 (PDE5) inhibitors (eg, sildenafil) or verapamil because severe dizziness, lightheadedness, or fainting may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Terazosin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Terazosin:


Use Terazosin as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Terazosin by mouth with or without food.

  • Terazosin may cause a sudden drop in blood pressure after the first dose. Take your first dose at bedtime. If you get up during the night, sit up slowly, then stand slowly.

  • If you miss a dose of Terazosin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.

Ask your health care provider any questions you may have about how to use Terazosin.



Important safety information:


  • Terazosin may cause drowsiness, dizziness, blurred vision, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Terazosin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Terazosin; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Terazosin may cause a sudden drop in blood pressure after the first dose. Take your first dose at bedtime. If you get up during the night, sit up slowly, then stand slowly. This will help to reduce your lightheadedness or dizziness. These effects are more likely to occur after the first few doses or if your dose has increased, but can occur at any time while you are taking the medicine. It can also occur if you stop taking the medicine and then restart treatment.

  • Terazosin may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.

  • Do NOT take more than the recommended dose without checking with your doctor.

  • Terazosin may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.

  • Tell your doctor or dentist that you take Terazosin before you receive any medical or dental care, emergency care, or surgery (including eye surgery).

  • Lab tests, including blood pressure, may be performed while you use Terazosin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Terazosin should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Terazosin while you are pregnant. It is not known if Terazosin is found in breast milk. If you are or will be breast-feeding while you use Terazosin, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Terazosin:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; drowsiness; lightheadedness; nasal congestion; nausea; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; chest pain; decreased sexual desire or ability; fainting; fast, slow, or irregular heartbeat;painful, prolonged erection; severe or prolonged dizziness or headache; shortness of breath; swelling of the ankles, feet, or hands.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Terazosin side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include dizziness; weakness.


Proper storage of Terazosin:

Store Terazosin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Terazosin out of the reach of children and away from pets.


General information:


  • If you have any questions about Terazosin, please talk with your doctor, pharmacist, or other health care provider.

  • Terazosin is to be used only by the patient for whom it is prescribed. Do not share it with other people. Do not use it for other health conditions.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • If using Terazosin for an extended period of time, obtain refills before your supply runs out.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Terazosin. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Terazosin resources


  • Terazosin Side Effects (in more detail)
  • Terazosin Use in Pregnancy & Breastfeeding
  • Drug Images
  • Terazosin Drug Interactions
  • Terazosin Support Group
  • 18 Reviews for Terazosin - Add your own review/rating


  • Terazosin Professional Patient Advice (Wolters Kluwer)

  • Terazosin Prescribing Information (FDA)

  • terazosin Advanced Consumer (Micromedex) - Includes Dosage Information

  • Hytrin Prescribing Information (FDA)

  • Hytrin Monograph (AHFS DI)

  • Hytrin Consumer Overview



Compare Terazosin with other medications


  • Benign Prostatic Hyperplasia
  • High Blood Pressure
  • Hyperhidrosis

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